Dr. Jacob Topfer, DO
Dr. Jacob Topfer is a board-certified anesthesiologist and fellowship-trained interventional pain management physician specializing in advanced regenerative and minimally invasive pain therapies. He trained at Nova Southeastern University and completed anesthesiology residency and a chronic pain fellowship at the University of Miami / Jackson Memorial Hospital.
Dr. Topfer has extensive experience with advanced neuromodulation techniques, including spinal cord and peripheral nerve stimulation, for patients with neuropathic or refractory pain. He uses both fluoroscopic and ultrasound guidance to perform interventional procedures with a focus on precision and safety.
He blends his foundation in traditional anesthesiology with cutting-edge regenerative therapies designed to treat pain at its source rather than simply masking symptoms. His approach centers on restoring function, improving performance, and enhancing quality of life with tailored, evidence-based treatment plans.
Dr. Topfer’s expertise also includes pain management with adjunct modalities such as IV ketamine, offering comprehensive care for complex pain conditions.
- Doctor of Osteopathic Medicine (DO) – Nova Southeastern University, Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, FL
- Bachelor of Science in Education, Exercise Physiology – University of Miami, Coral Gables, FL
- Graduate Coursework – University of Pennsylvania
- Medical License: Florida
- Medical License: New Jersey
- DEA License: Florida & New Jersey
- Board Certified – American Board of Anesthesiology
- Advanced Cardiac Life Support (ACLS)
- Pediatric Advanced Life Support (PALS)
- Basic Life Support (BLS)
- Fellowship: Chronic Pain Management – University of Miami / Jackson Memorial Hospital
- Residency: Anesthesiology – University of Miami / Jackson Memorial Hospital
Provides advanced interventional pain and regenerative therapies, including neuromodulation, image-guided injections, and minimally invasive spine procedures within a multidisciplinary regenerative medicine center.
Oversees evidence-based ketamine and integrative therapies for chronic pain and mood-related conditions, ensuring safety, protocol development, and coordinated patient care.
Provides anesthetic care across a wide range of surgical subspecialties with expertise in regional, neuraxial, and general anesthesia, as well as perioperative pain management.
Advanced training in interventional pain procedures, neuromodulation, and regenerative techniques at a high-volume academic pain center.
Comprehensive training in adult and pediatric anesthesia, regional techniques, critical care, and perioperative medicine in a tertiary academic medical center.
Provides anesthetic coverage and supports perioperative services across diverse practice settings and patient populations.
- Fishman M., Scherer A., Topfer J., Kim P. “Limited Access to On-Label Formulations of Buprenorphine for Chronic Pain.” Pain Medicine, 2019.
- Schwartz RH, Hernandez S, Noor N, Topfer J, et al. “A Comprehensive Review of the Use of Alpha-2 Agonists in Spinal Anesthetics.” Pain Physician, 2022.
- Topfer J, Abdallah RT. “Sacral Nerves.” In: Basic Anesthesiology Board Review, Oxford University Press (In Press).
- Decilveo AP, Szczech BW, Topfer J, Wittig JC. “Reconstruction Using Expandable Endoprostheses in Skeletally Immature Sarcoma Patients.” Orthopedics, 2017.
- Murray D, Topfer J, Decilveo AP, Wittig JC. “Early Diagnosis and Treatment of Soft Tissue Sarcomas of the Foot and Ankle.” J Foot Ankle Surg, 2016.
Poster presentations at major national and international meetings, including ASRA, ASPN, ASIPP, FSA, and MSTS conferences (2016–2022), covering topics in regional anesthesia, pain medicine, and musculoskeletal oncology.
Supported integrative and mindfulness-based programs for individuals managing trauma, stress, and chronic illness.
Provided medical care and anesthesia support to underserved communities in an international mission setting.
Helped organize educational events, workshops, and leadership initiatives for medical students interested in anesthesiology.
- General, regional, and monitored anesthesia care for all surgical subspecialties.
- Ultrasound-guided peripheral nerve blocks (interscalene, supraclavicular, femoral, sciatic, popliteal, TAP, ESP, PECS).
- Neuraxial anesthesia: spinal, epidural, and combined spinal-epidural techniques.
- Difficult airway management: video and fiberoptic intubation, advanced airway rescue techniques.
- Perioperative pain management and multimodal analgesia protocols.
- Fluoroscopic & ultrasound-guided injections: epidural, facet, medial branch, sympathetic, SI joint, and peripheral joints.
- Radiofrequency ablation (RFA) for facet and peripheral nerves.
- Spinal cord stimulation & peripheral nerve stimulation – trial and permanent implantation.
- Intrathecal pump trials, vertebral augmentation, MILD procedure, DRG stimulation.
- Epidural lysis of adhesions, diagnostic discography, selective nerve root blocks.
- Platelet-rich plasma (PRP) and stem cell therapies for musculoskeletal and neuropathic conditions.
- Prolotherapy and biologic joint restoration techniques.
- Integrative strategies for chronic pain and performance optimization.
- Pain management with adjunct modalities such as IV ketamine.
To discuss advanced interventional or regenerative options for chronic or neuropathic pain, schedule a consultation with our team.